Amazing Italian Penicillin Soup: 1 Comforting Recipe

October 22, 2025
Written By Leo Grant

Lorem ipsum dolor sit amet consectetur pulvinar ligula augue quis venenatis. 

There’s just something about a warm bowl of soup on a chilly day, isn’t there? Especially when you’re feeling a little under the weather. For me, nothing beats a good old-fashioned chicken pastina soup. It’s like a hug in a bowl! We always called it “Italian penicillin soup” growing up, because it just seemed to magically make everything better. It’s my absolute go-to when I need something simple, comforting, and healing. This homestyle chicken pastina soup is incredibly easy and tastes like it came straight from Nonna’s kitchen. Trust me, you’ll want this recipe in your rotation!

Why You’ll Love This Italian Penicillin Soup

This soup is a real winner for so many reasons. It’s ridiculously easy to whip up, even on those days when you have zero energy. Plus, the flavor is just pure comfort – warm, savory, and totally hug-in-a-bowl delicious. It’s perfect for:

  • Those sniffly sick days when you just need something gentle.
  • Cozy nights when the weather outside is frightful.
  • Busy weeknights when you need a quick, nourishing meal.
  • Anyone who loves classic, homestyle cooking!

Gathering Ingredients for Your Italian Penicillin Soup

Alright, let’s get our little comfort soup station ready! What I love about this Italian penicillin soup is that you probably have most of these things in your pantry right now. It’s all about simple, good-for-you ingredients that come together beautifully. Our founder Leo always says we’re about accessible ingredients, and this recipe is the perfect example! You’ll need some good quality chicken broth – about 8 cups to start. Then, two boneless, skinless chicken breasts, which we’ll cook right in the soup! For that classic tiny pasta goodness, we’re using 1 cup of acini di pepe. It just feels so right in this healing soup. Make sure you have about half a cup each of finely chopped carrots and celery, and a quarter cup of finely chopped onion – chopping these small is key for that homestyle feel you’re after.

Crafting the Perfect Italian Penicillin Soup: Step-by-Step

Okay, now for the fun part – actually making this glorious Italian penicillin soup! It’s really not complicated, and honestly, the simple steps are what make it so perfect for a day when you’re feeling a bit under the weather. We’re going for that delicious, homestyle feel here, so pay a little attention to how we chop those veggies. It makes all the difference! If you’re looking for more speedy meals like this, be sure to check out our collection of quick and easy dinners.

Sautéing the Aromatics for Your Italian Penicillin Soup

First things first, grab a nice big pot or a Dutch oven. Drizzle in about a tablespoon of olive oil and heat it up over medium heat. Now, toss in your finely chopped carrots, celery, and onion. Remember, we want these chopped pretty small so they’re tender and blend nicely into the soup. Cook ’em until they start to soften up, which usually takes about 5 to 7 minutes. Then, add in your minced garlic, dried oregano, and basil. Stir it all around for just another minute until you can smell that amazing fragrance – it’s the start of something good!

Simmering the Chicken and Broth

Time to pour in all that lovely chicken broth – we’re using 8 cups. Add your chicken breasts right into the pot, along with a good pinch of salt and some black pepper. Bring the whole thing up to a boil, then immediately turn the heat down to low. Let it simmer gently for about 15 to 20 minutes. You want to make sure that chicken is cooked all the way through. This is where all those good flavors start to meld together!

Shredding Chicken and Adding Pasta to Your Italian Penicillin Soup

Once the chicken is cooked, carefully take those breasts out of the pot and set them on a plate or cutting board. Let them cool just enough so you can handle them. Then, using two forks, shred the chicken nicely. It should come apart pretty easily. Now, throw that shredded chicken right back into the simmering broth. Give it a little stir, and then it’s pasta time! Bring the soup to a gentle boil again and add your 1 cup of acini di pepe pasta. Cook it according to the package directions, usually about 7 to 10 minutes, until it’s just right – tender but still a little bit chewy, or ‘al dente’ as they say.

Final Seasoning and Serving

This is the moment of truth! Taste your amazing Italian penicillin soup. Does it need a little more salt? A bit more pepper? Go ahead and adjust it until it tastes perfect to you. It’s your soup, make it exactly how you like it! Ladle generous bowls of this comforting soup, and don’t forget to garnish with some fresh chopped parsley. It just brightens everything up beautifully!

Tips for the Best Italian Penicillin Soup

Okay, so you’ve made the soup, but how do we take it from just good to *truly* amazing? Our founder, Leo, is all about finding those little efficiencies, like a project manager for your kitchen! He figured out that a few tiny tweaks can make a big difference in getting that perfect, comforting bowl every time. It’s all about making sure every step works for you, not the other way around! You can read more about his philosophy here.

Choosing the Right Pasta for Your Italian Penicillin Soup

While acini di pepe is my personal favorite for this Italian penicillin soup – those tiny little beads just feel so right! – don’t fret if you can’t find them. Orzo or even small ditalini work wonderfully. They all cook up quickly and give you that lovely texture in every spoonful.

Achieving a Homestyle Look

Want that perfectly cozy, homestyle vibe? It all comes down to the chop! Make sure your carrots, celery, and onion are diced really finely. Like, really small. It helps them cook tenderly and meld into the broth, giving the soup that classic, comforting texture that just feels like a hug.

Make-Ahead and Freezing Instructions for Italian Penicillin Soup

This Italian penicillin soup is a lifesaver for busy weeks, and guess what? It freezes like a dream! If you’re feeling run down, having a batch of this healing soup ready to go is pure genius. You can totally make it all the way through step 5 (before adding the pasta!), let it cool completely, and then pop it into freezer-safe containers. When you need it, just thaw it overnight in the fridge and then reheat it gently on the stovetop. Add the pasta when you reheat it so it doesn’t get mushy. It’s the ultimate sick day soup prep!

Frequently Asked Questions About Italian Penicillin Soup

Got questions about our favorite cozy soup? I get it! This Italian penicillin soup is such a go-to for so many reasons, and it’s normal to want to know a bit more. Here are some things people often ask:

What makes this Italian penicillin soup so comforting?

Oh, it’s pure magic! It’s the simple, gentle flavors, the warm broth, the tender chicken and pasta, all coming together. It’s like a warm hug from the inside out, perfect for when you need a little extra TLC.

Can I use different pasta shapes in this sick day soup?

Absolutely! While acini di pepe is my fave, feel free to use orzo, ditalini, or even tiny star pasta. Just cook it according to the package directions so it turns out nice and tender.

Is this Italian penicillin soup suitable for kids?

Totally! This chicken pastina soup is usually a huge hit with little ones. The flavors are mild, the pasta is tiny and fun, and it’s just so easy for them to eat and digest when they aren’t feeling their best.

Nutritional Information for Italian Penicillin Soup

You know, when Leo started Dishicious, he really wanted to make sure that even our simplest recipes felt balanced and achievable. This Italian penicillin soup is a perfect example! While exact numbers can vary based on your specific ingredients, a serving (about 1.5 cups) typically comes in around 350 calories, with about 35g of protein, 30g of carbs, and 10g of fat. It’s hearty and nourishing without being too heavy, and just what you need on a cozy night or a sick day. If you’re looking for more balanced meal ideas, especially for breakfast and brunch, check out our collection!

Share Your Italian Penicillin Soup Experience

I just LOVE hearing from you guys! If you whip up this cozy Italian penicillin soup, please let me know how it turned out. Did you try a different pasta? Did it work its magic on a sick day? Drop a comment below, give it a star rating, or share your own Nonna-approved tips with us. You can always reach out if you have questions too! Happy cooking!

Print

Italian Penicillin Soup (Chicken Pastina)

5 Stars 4 Stars 3 Stars 2 Stars 1 Star

No reviews

A comforting chicken and pastina soup, perfect for sick days or cozy nights. This recipe is easy to make and freezes well.

  • Author: leogrant
  • Prep Time: 15 min
  • Cook Time: 30 min
  • Total Time: 45 min
  • Yield: 6 servings 1x
  • Category: Soup
  • Method: Stovetop
  • Cuisine: Italian-American
  • Diet: Vegetarian

Ingredients

Scale
  • 8 cups chicken broth
  • 2 boneless, skinless chicken breasts
  • 1 cup acini di pepe pasta
  • 1/2 cup finely chopped carrots
  • 1/2 cup finely chopped celery
  • 1/4 cup finely chopped onion
  • 2 cloves garlic, minced
  • 1 tablespoon olive oil
  • 1 teaspoon dried oregano
  • 1/2 teaspoon dried basil
  • Salt and black pepper to taste
  • Fresh parsley, chopped (for garnish)

Instructions

  1. Heat olive oil in a large pot or Dutch oven over medium heat. Add chopped carrots, celery, and onion. Cook until softened, about 5-7 minutes.
  2. Add minced garlic, oregano, and basil. Cook for 1 minute more until fragrant.
  3. Pour in chicken broth. Add chicken breasts, salt, and pepper. Bring to a boil, then reduce heat and simmer for 15-20 minutes, or until chicken is cooked through.
  4. Remove chicken breasts from the pot. Shred the chicken using two forks, then return it to the pot.
  5. Bring the soup back to a gentle boil. Add acini di pepe pasta and cook according to package directions, usually 7-10 minutes, until al dente.
  6. Taste and adjust seasoning with salt and pepper if needed.
  7. Ladle soup into bowls and garnish with fresh parsley.

Notes

  • For a homestyle look, ensure your vegetables are finely chopped.
  • This soup freezes well. Let it cool completely before transferring to airtight containers. Reheat gently on the stovetop.
  • You can use other small pasta shapes like orzo or ditalini if acini di pepe is unavailable.

Nutrition

  • Serving Size: 1.5 cups
  • Calories: 350
  • Sugar: 5g
  • Sodium: 800mg
  • Fat: 10g
  • Saturated Fat: 2g
  • Unsaturated Fat: 8g
  • Trans Fat: 0g
  • Carbohydrates: 30g
  • Fiber: 3g
  • Protein: 35g
  • Cholesterol: 90mg

Did you make this recipe?

Share a photo and tag us — we can't wait to see what you've made!

Leave a Comment

Recipe rating 5 Stars 4 Stars 3 Stars 2 Stars 1 Star